Adewole was born in Ondo City, Ondo State, on January 8, 1972. Between 1978 and 1983, he attended St. Stephen Primary School in Ondo.

From 1983 to 1989, he attended St. Joseph College in Ondo. From 1991 to 1997, he attended Obafemi Awolowo University, where he earned a law degree.

Adebayo is a public affairs commentator who provides advice on national issues on occasion and participates in Nigerian politics as a member of the Third Force.

On January 15, 2022, Adewole Adebayo declared his intention to run for the office of the Nigerian president. He is running for president of Nigeria in the 2023 Nigerian general election under the Social Democratic Party.

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