24 teams confirmed their places at the rescheduled 2023 Africa Cup of Nations set to take place in Ivory Coast next year.
The competition will take place between January 13 and February 11, posing a big challenge to the top European Leagues, who have African players as their leading stars.
Napoli is set to be one of the most affected clubs in Europe, with Victor Osimhen set to lead the Super Eagles charge. Osimhen was key to the Partenopei's title charge last season. Rudi Garcia will also have to do without his midfield lynchpin Zambo Frank Anguissa, who is set to be called up by Cameroon.
English Premier League clubs will also suffer the same fate. Erik ten Hag will have to do without new first-choice goalkeeper Andre Onana, whose reconciliation with Cameroon's Head Coach Rigobert Song will see him stand in between the sticks as the Indomitable Lions chase a sixth title.
Jurgen Klopp used to suffer back in the days when Mohamed Salah and Sadio Mane would leave, but since the latter is no longer at the club, the German will have to figure out a way of remaining competitive without his Egyptian marksman.
Which EPL players will possibly feature at AFCON?
We take a look at all the African players in the Premier League who are eligible for a call-up ahead of the October 12 draw. The list contains all players who come from African nations, irrespective of whether or not they have ever received call-ups.
1. Tottenham Hotspur
Yves Bissouma(Mali)
Pape Sarr(Senegal)
2. Liverpool
Mohamed Salah(Egypt)
3. West Ham
Said Benrahma(Algeria)
Nayef Aguerd(Morocco)
Mohamed Kudus(Ghana)
4. Arsenal
Thomas Partey(Ghana)
Mohamed Elneny(Egypt)
5. Brighton
Tariq Lamptey(Ghana)
Carlos Baleba(Cameroon)
6. Crystal Palace
Cheick Doucure(Mali)
Jordan Ayew(Ghana)
7. Brentford
Bryan Mbeumo(Cameroon)
Frank Onyeka (Nigeria)
Yoane Wissa (DR Congo)
8. Nottingham Forest
Ola Aina (Nigeria)
Serge Aurier, Willy Boly, Ibrahim Sangare (Ivory Coast)
Moussa Niakhate, Cheikhou Kouyate (Senegal)
Taiwo Awoniyi, Emmanuel Dennis (Nigeria)
9. Aston Villa
Bertrand Traore (Burkina Faso)
10. Manchester United
Andre Onana (Cameroon)
Soyfan Amrabat (Morocco)
Hannibal Mejbri (Tunisia)
Amad Diallo (Ivory Coast)
11. Chelsea
Nicolas Jackson (Senegal)
12. Fulham
Calvin Bassey, Alex Iwobi (Nigeria)
Fode Ballo-Toure (Senegal)
13. Wolverhampton Wanderers
Ait Rayan Nouri (Algeria)
Boubacar Traore (Mali)
14. Bournemouth
Hamed Junior Traore (Ivory Coast)
Dango Outtara (Burkina Faso)
Antoine Semenyo (Ghana)
15. Sheffield United
Ismailla Coulibaly (Mali)
16. Everton
Abdoulaye Doucore(Mali)
17. Luton
Issa Kabore (Burkina Faso)
Pelly-Ruddock Mpanzu(DR Congo)
18. Burnley
Bastien Samuel (DR Congo)
Zaroury Anass (Morocco)
Lyle Forster (South Africa)